According to a recent study, carpal tunnel syndrome might be an early sign of transthyretin amyloid cardiomyopathy (ATTR-CM), a type of cardiac amyloidosis known as “stiff heart syndrome.”

The research, published in Mayo Clinic Proceedings, found that patients with carpal tunnel syndrome had a higher prevalence of amyloid deposits in their tissue. The link was especially true for people having carpal tunnel release surgery.1 As a result, people with carpal tunnel have three times the risk of developing amyloidosis compared to those without carpal tunnel syndrome. They also have a 13% greater risk of heart failure.

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