New health care innovations and technologies are emerging rapidly, and the Current Procedural Terminology (CPT®) 2025 code set will help physicians keep pace with this quickly evolving landscape with the release of its new edition which contains 420 updates for 2025.

Published by the AMA, the CPT code set is often described as the “language of medicine,” and the more than 11,000 CPT codes in use today serve as the standardized terminology for communicating the use of medical, surgical and diagnostic services across health care. These codes are also the foundation for how health care procedures are tracked, reimbursed and studied.

Descriptors attached to the codes are incorporated into medical documents, insurance forms, price sheets and patient portals and serve as important resources for many hospitals, health plans and medical offices.

“The latest updates to the CPT code set reflect advancements in contemporary clinical practice and ensures the code set fulfills its vital role as the trusted universal language of medicine,” said AMA President Bruce A. Scott, MD, a private practice otolaryngologist in Louisville, Kentucky.

The 420 updates contained in the CPT 2025 code set include 270 new codes, 112 deletions and 38 revisions. These changes reflect the expansion into new areas of medicine—as the highest proportion of new codes (37%) involve proprietary laboratory analyses and most of these are related to novel genetic testing.

Category III CPT codes, which are temporary and used for emerging technologies, services and procedures, accounted for 30% of the new codes.

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